The "Born This Way" singer was looking fashionable in a yellow and black frock as she exited her temporary digs at the Chateau Marmont Hotel in West Hollywood.
After making a quick appearance for photographers and fans, Gaga was escorted to a nearby airport to board a private jet en route to an unknown destination.
Meanwhile, the 25-year-old took to Twitter during the day while posting a message reading, "Less than a week."
The unspecified posting is thought to be in regards to her music video for the latest single "You and I" - which she previously said would be released via her 1000th tweet - with the most recent message having been her 994th entry on the popular social networking site.
Enjoy the pictures of Lady Gaga as she leaves the Chateau Marmont Hotel in West Hollywood, Ca (August 13).